Introducing an innovative, systematic approach to understanding differential diagnosis, trains students and other learners to think like clinicians and master the methodology behind diagnosing the most commonly encountered conditions in internal medicine.

This source for internal medicine and the care of adult patients includes the diagnosis and treatment of thousands of common and uncommon conditions, always guided by an understanding of the epidemiology and pathobiology, as well as the latest medical literature.

The latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, demonstrative full-color drawings, and practical clinical decision trees and algorithms.

**Not all chapters in the 21st edition have been included in this edition, yet.**
The latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, demonstrative full-color drawings, and practical clinical decision trees and algorithms.

Concise tables and figures summarize treatment protocols, drug details, and other essential information for fast, efficient review.

An evidence-based, step-by-step process for evaluating, diagnosing, and treating patients based on their clinical complaints. Each chapter addresses one common complaint and begins with a case and guidance on how to organize the differential diagnosis.